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Oocyte-associated transcription factors in reprogramming after somatic cell nuclear transfer: a review

Fengxia YIN,Hui LIU,Shorgan BOU,Guangpeng LI

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 104-113 doi: 10.15302/J-FASE-2014003

Abstract: The reprogramming of the somatic nucleus from its original cellular state to a totipotent state is essentialfor term development after somatic cell nuclear transfer.The nuclear-associated factors contained within oocytes are critical for normal fertilization by spermor for somatic cell nuclear reprogramming.The chromatin of somatic nuclei can be reprogrammed by factors in the egg cytoplasm whose natural function

Keywords： nuclear reprogramming     somatic cell     transcription factors     transcriptomics    

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Factors influencing the somatic cell nuclear transfer efficiency in pigs

Yong JIN, Manling ZHANG, Xinrong JU, Shuang LIANG, Qiang XIONG, Lihua ZHAO, Xiaowei NIE, Daorong HOU, Qiang LIU, Junzheng WANG, Chenyu WANG, Xiaokang LI, Lining ZHANG, Xiaorui LIU, Ying WANG, Haiyuan YANG, Yifan DAI, Rongfeng LI

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 73-80 doi: 10.15302/J-FASE-2018220

Abstract: The results demonstrated that cells at high confluence (>90%) used as donor cell resulted in higherThe number of blastocysts transferred by somatic cell nuclear transfer (SCNT) did not significantly affectthe cloning efficiency, but transfer of blastocyst derived from culture 5 d after SCNT achieved a significantlyhigher pregnancy rate compared with one to two cell SCNT embryos from overnight culture.

Keywords： blastocyst     donor cell     estrus synchronization     pregnancy rate     pig cloning     somatic cell nuclear transfer    

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Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 33-41 doi: 10.15302/J-FASE-2018228

Abstract: Meanwhile, early embryo development is significant for somatic cell nuclear transfer in cattle as a large

Keywords： bovine cloning     embryo development     somatic cell nuclear transfer     X-inactive specific transcript    

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The ecological adaptability of cloned sheep to free-grazing in the Tengger Desert of Inner Mongolia, China

Xinxin LI,Huijuan WANG,Guanghua SU,Zhuying WEI,Chunling BAI,Wuni-MENGHE,Yanhui HOU,Changqing YU,Shorgan BOU,Guangpeng LI

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 191-200 doi: 10.15302/J-FASE-2014029

Abstract: Since the birth of the first cloned sheep, somatic cell nuclear transfer technology has been successfully

Keywords： somatic cell nuclear transfer     free-grazing synchronization     Dorper sheep     cloned animal ecology    

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Adoptive cell transfer therapy for hepatocellular carcinoma

Renyu Zhang, Zhao Zhang, Zekun Liu, Ding Wei, Xiaodong Wu, Huijie Bian, Zhinan Chen

Frontiers of Medicine 2019, Volume 13, Issue 1,   Pages 3-11 doi: 10.1007/s11684-019-0684-x

Abstract: The antitumor activities of adoptive cell transfer therapy (ACT), such as strategies based on tumor-infiltratingCurrently, chimeric antigen receptor T-cell (CAR-T) immunotherapy has achieved numerous breakthroughshematological malignancies, including relapsed or refractory lymphoblastic leukemia and refractory large B-cell

Keywords： adoptive cell transfer therapy     hepatocellular carcinoma     T cell     chimeric antigen receptor     immunotherapy    

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Potential of electron transfer and its application in dictating routes of biochemical processes associated

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 679-692 doi: 10.1007/s11684-021-0866-1

Abstract: of reduction of a compound, we have recently proposed a calculation termed as potential of electron transferEnabling electron transfer could drive metabolic reprogramming in cancer metabolism.Therefore, the concept and model established on electron transfer could guide the treatment strategies

Keywords： metabolic reprogramming     potential of electron transfer     cell proliferation     aerobic glycolysis     cancer    

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Challenges of NK cell-based immunotherapy in the new era

Fang Fang, Weihua Xiao, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 440-450 doi: tzg@ustc.edu.cn

Abstract: Various cellular sources, including peripheral blood mononuclear cells (PBMCs), stem cells, and NK cellHowever, considering the safety, activities, and reliability of the cell products, researchers must developIn this review, the challenges on NK cell-based therapeutic approaches and clinical outcomes are discussed

Keywords： natural killer cells     immunotherapy     adoptive transfer     genetic modification     immune checkpoint inhibitor    

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Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60

Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 323-328 doi: 10.1007/s11684-010-0026-5

Abstract: This study explored the effects of nuclear factor-kappa B (NF-κB) inhibitor Bay 11-7082 on Fas/FasL systemand Fas-mediated apoptosis in cell line HL-60 cells.

Keywords： nuclear factor-kappa B     Fas/FasL system     HL-60     Bay 11-7082    

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Special issue: innovative nuclear energy technology

Frontiers in Energy 2021, Volume 15, Issue 4,   Pages 791-792 doi: 10.1007/s11708-021-0794-4

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An old issue and a new challenge for nuclear reactor safety

F. D’AURIA

Frontiers in Energy 2021, Volume 15, Issue 4,   Pages 854-859 doi: 10.1007/s11708-021-0729-0

Abstract: Nuclear reactor safety (NRS) and the branch accident analysis (AA) constitute proven technologies: theseamong the other things, long lasting research and operational experience in the area of water cooled nuclearWeaknesses became evident, noticeably in relation to nuclear fuel under high burn-up.

Keywords： large break loss of coolant accident (LBLOCA)     nuclear reactor safety (NRS)     licensing perspectives     basisfor design of water cooled nuclear reactors (WCNR)    

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Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 79-90 doi: 10.1007/s11684-020-0783-8

Abstract: cells, a type of cytotoxic lymphocytes, can infiltrate into ischemic brain and exacerbate neuronal cellStrikingly, ASIV reversed NK cell deficiency in the spleen and blood after brain ischemia.ASIV restored acetylation of histone H3 and the p65 subunit of nuclear factor-κB in the ischemic brainSimultaneously, ASIV prevented p65 nuclear translocation.The effects of ASIV on reducing CCL2 production, restoring acetylated p65 levels and preventing p65 nuclear

Keywords： astragaloside IV     brain ischemia     natural killer cells     histone deacetylase     nuclear factor-κB    

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Let Nuclear Technology Create New Brilliancy forChina’s Sustainable Development

Du Xiangwan

Strategic Study of CAE 2008, Volume 10, Issue 1,   Pages 9-11

Abstract:

This paper summarizes the development and application directions of nucleartechnology, including five aspects: nuclear technology and energy、nuclear technology and medicine,nuclearanalysis technology,nuclear radiation technology,astronautics and voyage´s nuclear power,etc.discusses the importance of them to sustainable development and generalizes the development trilogy of nuclear

Keywords： nuclear science     nuclear technology     nuclear engineering     sustainable development    

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Reliability prediction and its validation for nuclear power units in service

Jinyuan SHI,Yong WANG

Frontiers in Energy 2016, Volume 10, Issue 4,   Pages 479-488 doi: 10.1007/s11708-016-0425-7

Abstract: In this paper a novel method for reliability prediction and validation of nuclear power units in serviceUsing these factors, the equivalent availability factor of nuclear power units in the following 3 yearsFurthermore, the reliability prediction method is validated using the nuclear power units in North AmericanIt is found that the relative errors of the predicted equivalent availability factors for nuclear powerfollowing 3 years, thus providing effective reliability management and maintenance optimization methods for nuclear

Keywords： nuclear power units in service     reliability     reliability prediction     equivalent availability factors    

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A Chinese–French Study on Nuclear Energy and the Environment Feature Article

Xiangeng Zhao, Qizhen Ye, Sébastien Candel, Dominique Vignon, Robert Guillaumont

Engineering 2023, Volume 26, Issue 7,   Pages 159-172 doi: 10.1016/j.eng.2023.04.011

Abstract:

This article focuses on the environmental impact of nuclear energy andaddresses the following major environmental issues associated with nuclear power generation: ① controllingaccidents and their radioactive releases and; ④ improving nuclear safety to restrict its environmentalimpact and to contribute toward the public acceptance of nuclear energy.The annual effective radiation dose delivered to the public surrounding nuclear power plants under normal

Keywords： Nuclear energy     Environmental impact     Radwaste management     Severe nuclear accidents     Nuclear safety    

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Sustainable Development of Chinses Nuclear Power

Zhao Renkai

Strategic Study of CAE 2000, Volume 2, Issue 10,   Pages 33-41

Abstract:

Nuclear power is considered a sustainable energy resource, and it is a very important pillar for theIn the paper, the present status of nuclear power development in the world and China is described.The general and specific policies and technical route for Chinese nuclear power development, and severalproblems commonly concerned with Chinese nuclear power development, such as uranium resources、nuclearsafety、radioactive wastes and localization of nuclear power in China are expounded and analyzed.

Keywords： nuclear energy     uranium resources     nuclear safety     radioactive westes     localization    

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Title Author Date Type Operation

Oocyte-associated transcription factors in reprogramming after somatic cell nuclear transfer: a review

Fengxia YIN,Hui LIU,Shorgan BOU,Guangpeng LI

Journal Article

Factors influencing the somatic cell nuclear transfer efficiency in pigs

Yong JIN, Manling ZHANG, Xinrong JU, Shuang LIANG, Qiang XIONG, Lihua ZHAO, Xiaowei NIE, Daorong HOU, Qiang LIU, Junzheng WANG, Chenyu WANG, Xiaokang LI, Lining ZHANG, Xiaorui LIU, Ying WANG, Haiyuan YANG, Yifan DAI, Rongfeng LI

Journal Article

Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Journal Article

The ecological adaptability of cloned sheep to free-grazing in the Tengger Desert of Inner Mongolia, China

Xinxin LI,Huijuan WANG,Guanghua SU,Zhuying WEI,Chunling BAI,Wuni-MENGHE,Yanhui HOU,Changqing YU,Shorgan BOU,Guangpeng LI

Journal Article

Adoptive cell transfer therapy for hepatocellular carcinoma

Renyu Zhang, Zhao Zhang, Zekun Liu, Ding Wei, Xiaodong Wu, Huijie Bian, Zhinan Chen

Journal Article

Potential of electron transfer and its application in dictating routes of biochemical processes associated

Journal Article

Challenges of NK cell-based immunotherapy in the new era

Fang Fang, Weihua Xiao, Zhigang Tian

Journal Article

Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60

Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU

Journal Article

Special issue: innovative nuclear energy technology

Journal Article

An old issue and a new challenge for nuclear reactor safety

F. D’AURIA

Journal Article

Astragaloside IV suppresses post-ischemic natural killer cell infiltration and activation in the brain

Baokai Dou, Shichun Li, Luyao Wei, Lixin Wang, Shiguo Zhu, Zhengtao Wang, Zunji Ke, Kaixian Chen, Zhifei Wang

Journal Article

Let Nuclear Technology Create New Brilliancy forChina’s Sustainable Development

Du Xiangwan

Journal Article

Reliability prediction and its validation for nuclear power units in service

Jinyuan SHI,Yong WANG

Journal Article

A Chinese–French Study on Nuclear Energy and the Environment

Xiangeng Zhao, Qizhen Ye, Sébastien Candel, Dominique Vignon, Robert Guillaumont

Journal Article

Sustainable Development of Chinses Nuclear Power

Zhao Renkai

Journal Article